Arterial wall response to injury and healing
نویسندگان
چکیده
منابع مشابه
Platelet P2Y(12) receptor influences the vessel wall response to arterial injury and thrombosis.
BACKGROUND Platelets are believed to play an important role in atherogenesis and the vessel response to vascular injury. The P2Y(12) receptor (P2Y(12)) plays a central role in amplifying platelet aggregation, dense granule and alpha-granule secretion, P-selectin expression, microparticle formation, and procoagulant membrane changes, regardless of the activating stimulus. We hypothesized that P2...
متن کاملThe Electrical Response to Injury: Molecular Mechanisms and Wound Healing.
Significance: Natural, endogenous electric fields (EFs) and currents arise spontaneously after wounding of many tissues, especially epithelia, and are necessary for normal healing. This wound electrical activity is a long-lasting and regulated response. Enhancing or inhibiting this electrical activity increases or decreases wound healing, respectively. Cells that are responsible for wound closu...
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Introduction: Arterial stiffness is an important predictor of cardiovascular risk. Several indices have been introduced to estimate the arterial stiffness based on the changes in the brachial blood pressure. Since the substitution of the blood pressure changes in the central arteries such as carotid with the blood pressure changes in the brachial results in error in the blood...
متن کامل712 Platelets , Vasoconstriction , and Nitroglycerin During Arterial Wall Injury
Endothelial injury in vivo is associated with platelet deposition and a localized plateletdependent vasoconstrictive response. To assess the influence of nitroglycerin on platelets and vasoconstriction, quantitative `111n-labeled platelet deposition (no platelets x 106/cm2) of the injured segment and the degree of angiographic vasoconstriction (percent diameter narrowing proximal and distal to ...
متن کاملPlatelets , Vasoconstriction , and Nitroglycerin During Arterial Wall Injury
Endothelial injury in vivo is associated with platelet deposition and a localized plateletdependent vasoconstrictive response. To assess the influence of nitroglycerin on platelets and vasoconstriction, quantitative `111n-labeled platelet deposition (no platelets x 106/cm2) of the injured segment and the degree of angiographic vasoconstriction (percent diameter narrowing proximal and distal to ...
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ژورنال
عنوان ژورنال: Journal of Vascular Surgery
سال: 1989
ISSN: 0741-5214
DOI: 10.1016/0741-5214(89)90061-x